Furosemide is a loop diuretic. The active ingredient is dispensed as oral tablets (20mg, 40mg and 80mg) and an oral solution.

Brand names of Furosemide: Aluzine, Dryptal, Froop, Frumax, Frumil, Frusetic, Frusid, Frusol, Lasix, Rusyde, Tenkafruse.

Drug Uses

Furosemide is used to treat fluid retention that often occurs in patients with liver or kidney disease, and congestive heart failure. The excess fluid is eliminated from the body by urination. Furosemide also prevents the body from absorbing excessive amounts of salt.

Furosemide is used to treat other medical conditions not listed in this information guide.


Furosemide must always be used as directed. Do not make adjustments to the dose before speaking to a doctor.

If using the oral solution ensure that each dose is measured using a proper medical measuring device to ensure that the correct dosage is dispensed.

Missed Dose

Furosemide is sometimes taken when required so this will not apply. If, however, your are on a scheduled dosage and you miss a dose, it may be taken when you remember. However, do not take the missed dose near the time of the next scheduled dose. In this case, ignore the missed dose. Never double-up on a dose.

Warnings and Precautions

Do not use Furosemide if you are allergic to furosemide.

Tell your doctor if you suffer with any of the following: gout, diabetes, lupus, liver or kidney disease, or if you are allergic to sulfa drugs.

While using Furosemide you will need to have regular blood tests to ensure that the medication is having the desired effect. Your doctor may also wish to regularly check that your liver and kidneys are functioning correctly.

Furosemide is likely to cause increased urination, so ensure that you do not get dehydrated. Drink plenty of fluids. Ask your doctor about eating foods with a high content of potassium, or taking potassium supplements.

If you are using Furosemide to treat high blood pressure, do not stop taking this medication even if you are feeling fine. There are often no obvious symptoms of high blood pressure.

It is not known if Furosemide is harmful to an unborn fetus, so pregnant women should use this drug with caution. Women who are breast-feeding should also use Furosemide with caution as this drug passes into breast milk.

Before using Furosemide, you must give your doctor full details of your medical history and other medications that you use. These include herbal medicines and vitamin supplements. Furosemide can react badly with some medications.

Possible Side-effects

Get emergency help if any of the following symptoms of allergy occur: hives, difficulty in breathing, or swelling of the face, tongue, lips or throat.

Contact your doctor immediately if any of the following side-effects occur: nausea or vomiting, weakness, drowsiness, thirst, restlessness, lightheadedness, fast or irregular heartbeat, decreased urination, muscle pain, easy bleeding or bruising, skin rash (with peeling or blistering), stomach pain, lack of appetite, low fever, clay-colored stools, dark urine, or jaundice.

Less serious side-effects may include stomach pain, headache, diarrhea or constipation, numbness, dizziness, vision problems, or burning or tingling sensation.

Contact your doctor if any uncomfortable symptoms occur, or persist.


Call for emergency help immediately. Symptoms of overdose can include lack of appetite, weakness, dizziness, ringing in the ears, confusion, or fainting.

Storage instructions

Furosemide must be kept away from children and stored in a dry, cool place away from sunlight and moisture.

What are diuretics?

Diuretics are drugs that enable the body to get rid of excess fluids, via urination. Commonly called "water pills", some diuretics are available over-the-counter while others require a doctor's prescription.

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Everybody require enough water in their bodies in order to carry out several important tasks. The recommended amount, on a daily basis, is six to eight glasses however during summer, one requires to take more water since there is increased water loss through. A dehydrated body has several health implications and is also responsible for a dry and scaly skin. Below are some reasons why having a properly hydrated skin is essential.

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Dehydration in Men

Dehydration refers to a condition where the body lacks water because water exiting the body far exceeds the water entering the body. We tend to lose water in many ways due to activities like breathing, urinating, sweating etc. And this balance of water loss needs to be maintained by consuming lots of fluids.

In most cases, this situation can easily be reversed by increasing the intake of fluids, but in some extreme cases, immediate medical attention is required. Men comparatively suffer more from dehydration because they are more inclined to physical activity. The rate at which men tend to lose bodily fluids is far higher to that compared to women. Dehydration can either be mild, moderate or severe, depending on the loss of body fluids which happen. And, severe dehydration can also cause death in worst of cases.


There are several reasons due to which dehydration can happen. The most common of them are:

  • Fever
  • Increased rate of urination ( which might happen due to uncontrolled diabetes or some medical condition)
  • Too much of sweating due to physical exercise
  • Vomiting or diarrhoea
  • Limited access to safe drinking water
  • Presence of mouth sores or having a sore throat

Elderly men with diseases like diabetes are at a higher risk of suffering from dehydration.


Several symptoms of mild to moderate dehydration tend to be as follows:

  • Not urinating much
  • Dry, cool skin
  • Headache
  • Muscle cramps
  • Dry or sticky mouth
  • Thirst
  • Darker yellow urine

Signs for severe dehydration tend to be as follows:

  • Not urinating at all
  • Amber coloured or extremely dark yellow urine
  • Irritability or confusion
  • Rapid heartbeat
  • Sunken eyes
  • Listlessness
  • Shock (reduced blood flow through the body)
  • Rapid Breathing
  • Dry, shrivelled skin
  • Dizziness or light-headedness
  • Unconsciousness or delirium


The physician performs both physical and mental examinations for the diagnosis of dehydration. And through these diagnoses, conclusions can be drawn out.

Blood tests are often employed in mento test the kidney functions in case of dehydration along with checking for the potassium, sodium and other electrolyte levels. Even urinalysis is helpful in providing useful information during the course of the diagnosis, where the urine tends to be darker and more concentrated while containing a certain amount of ketone compound


For treating dehydration:

  • Drink adequate water.
  • If possible, drink sports drinks that contain electrolytes.
  • Do not consume salt tablets. They tend to result in some serious complications
  • Consuming Intravenous fluids
  • Avoiding drinking items containing high amounts of caffeine like tea, coffee, and soda
  • Consuming certain medications (such as anti-diarrhoea medicines, anti-emetics and anti-fever medicines)


There are few things that one should be kept in mind to avoid getting dehydrated. These are:

  • Drink lots and lots of fluids everyday, especially so on sunny and hot days or when you are exercising.
  • In case of vomiting or diarrhoea, do not wait for the signs of dehydration. Consume more amounts of fluids to balance the outflow of the liquid.
  • Having a healthy diet with a lot of fruits and vegetables

These are some of the ways in which dehydration can be avoided. In case of dehydration, elderly men need to be given a special attention to. They are more at a risk and hence they should often be given more water and other fluids if required on a timely basis.

Neuromuscular blockers + Frusemide (Furosemide)

The effects of the neuromuscular blockers may be increased by low doses of frusemide but opposed by higher doses.

Clinical evidence

Three patients receiving kidney transplants showed increased neuromuscular blockade with tubocuranne (seen as a pro¬nounced decrease in twitch tension) when given frusemide (40 or 80 mg) and mannitol (12 5 mg) intravenously. One of them showed the same reaction when later given only 40 mg frusemide but no mannitol. The residual blockade was easily antagonized with pyndostigmine (14 mg) or neostigmine (3 mg) with atropme (1 2 mg).

10 patients given 1 mg/kg frusemide took 14 7 mm to recover from 95 to 50% blockade with pancuroraum (as measured by a twitch response) compared with 21 8 mm in 10 other patients who had had no frusemide.


Uncertain Animal studies indicate that what happens probably depends on the dosage of frusemide 0 1-10 (ig/kg increased the blocking effects of tubocuranne and suxamethomum whereas 1-4 mg/kg opposed the blockade. One suggestion is that low doses of frusemide inhibit protein kmase, whereas higher doses cause inhibition of phosphodiesterase.

Importance and management

The documentation is very limited. Be on the alert for changes in the response to any blocker if frusemide is used Animal studies suggest that increases occur with doses less than 10 ugl kg, but decreases with doses of 1-4 mg/ kg. Whether these same changes occur if frusemide is given orally seems not to have been studied.

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